Pilomaricoma is a relatively rare and almost benign skin tumor with hair cortex cell, defferentiation. We conducted a clinico-histopathologic study with cases of biopsy-proven pilomatricoma, which appeared at the histopathology files of
Department
of
Dermatology. Wonkwang University Hospital during last 12 years.
@ES The results were as follows:
@EN 1. In the age distribution, the patients lesser than 20 years old consisted 9 cases(69%). The mean age was 18 years old. The ratio of males to females was 1: 3.3. The duration of the lesions was from 1 month to 9 years. with the mean duration
of 15
months. The predilection sites were the face(54%), arm, neck, thigh, chest, axilla in order.
2. All lesions were hard in consistency, and were from bean to walnut sized. Clinically, 4 cases(31%) showed red to bluish discoloration and/or anetodermic cutaneous changes. Four cases(31%) showed multiple skin lesions.
3. At the first presentation, we considered the tumor as follows clinically; pilomatricoma, epidermal cyst, calcinosis cutis, steatocystoma multiplex, and other benign cutaneous tumor.
4. Histopathologically, the typical patterns of pilomatricoma were commonly located at the dermis(13 cases) and consisted of the basophilic cells and shadow cells. However, most of the tumors were composed largely of shadow cells. The tumors(11
cases)
showed the transition of basophillic cells into shadow cells.
In many tumors(12 cases), small round, eosinophillic centers of keratinization are seen within aggregation of shadow cells.
5. The stroma of the tumor(10 cases) usually presented considerable chronic inflammatory infiltrates and foreign body reactions adjacent to the shadow cells.
6. With the von Kossa stain, calcium deposits are found in 85% of the tumors.
7. In all cases, excisional biopsy have been done for the diagnosis and therapy.
|